Document Type

Journal Article

Publication Title

International Journal of Environmental Research and Public Health

Volume

18

Issue

4

First Page

1

Last Page

24

Publisher

MDPI

School

School of Nursing and Midwifery

RAS ID

35623

Comments

Arabiat, D., Jabery, M. A. L., Kemp, V., Jenkins, M., Whitehead, L. C., & Adams, G. (2021). Motor developmental outcomes in children exposed to maternal diabetes during pregnancy: A systematic review and meta-analysis. International Journal of Environmental Research and Public Health, 18(4), article 1699. https://doi.org/10.3390/ijerph18041699

Abstract

© 2021 by the author. Licensee MDPI, Basel, Switzerland. Studies on the association of maternal diabetes with motor development in children provide inconsistent findings. We searched MEDLINE/PubMed, EMBASE, Emcare, PsycINFO, and Google Scholar databases for primary observational, case–control, or cohort studies that report on the motor development of children exposed to maternal diabetes during pregnancy. Quality appraisal and data extraction were performed independently and in duplicate. A meta-analysis of summary measures was performed using random-effect models. Eighteen studies were identified for inclusion, however, only 13 were included in the meta-analysis. Exposure to maternal diabetes during pregnancy was associated with a lower pooled motor development in children and a decrease in both gross and fine motor development. Among all other factors, pre-existing diabetes and other gestational comorbidities, such as hypertension and obesity, or low socioeconomic status, also affect child development. Therefore, among children of diabetic mothers, those with other gestational comorbidities or pre-existing diabetes were more likely to be at risk developmentally.

DOI

10.3390/ijerph18041699

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

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