Pick me, pick me! Rationale for investigating persistent inward currents (PICs) and associated exercise effects in the ageing neuromuscular system
Abstract
The loss of neuromuscular function with ageing has been extensively documented. Physiologically, muscular fibre atrophy, loss and denervation along with associated motor unit remodelling occur with, and continue into, ageing. Although motor unit remodelling serves to reinnervate and preserve local muscle fibres and thus function, overall reductions in muscle strength and power are linked to greater risk of falling, associated co‐morbidities and all‐cause mortality amongst elderly individuals.
RAS ID
36171
Document Type
Other
Date of Publication
2021
PubMed ID
33491208
School
School of Medical and Health Sciences
Copyright
free_to _read
Publisher
Wiley
Comments
Latella, C. (2021). Pick me, Pick me! Rationale for investigating persistent inward currents (PICs) and associated exercise effects in the ageing neuromuscular system. The Journal of Physiology, 599(7), 1957-1959. https://doi.org/10.1113/JP281324