Pick me, pick me! Rationale for investigating persistent inward currents (PICs) and associated exercise effects in the ageing neuromuscular system
Document Type
Other
Publication Title
Journal of Physiology
PubMed ID
33491208
Publisher
Wiley
School
School of Medical and Health Sciences
RAS ID
36171
Abstract
The loss of neuromuscular function with ageing has been extensively documented. Physiologically, muscular fibre atrophy, loss and denervation along with associated motor unit remodelling occur with, and continue into, ageing. Although motor unit remodelling serves to reinnervate and preserve local muscle fibres and thus function, overall reductions in muscle strength and power are linked to greater risk of falling, associated co‐morbidities and all‐cause mortality amongst elderly individuals.
DOI
10.1113/JP281324
Access Rights
free_to _read
Comments
Latella, C. (2021). Pick me, Pick me! Rationale for investigating persistent inward currents (PICs) and associated exercise effects in the ageing neuromuscular system. The Journal of Physiology, 599(7), 1957-1959. https://doi.org/10.1113/JP281324