Abstract
Falls and cardiovascular disease (CVD) are continuing to be a significant public concern, requiring a better understanding of their shared risk factors and underpinning mechanisms. While previous, mostly cross-sectional studies, indicate a link between CVD, musculoskeletal health, and falls, their relationships remain poorly understood. This thesis sought to examine the association between clinical/subclinical CVD, musculoskeletal health, injurious falls and fractures. By drawing evidence from multiple publications, including reviews and studies from a prospective cohort, this thesis reports associations between CVD, musculoskeletal outcomes, and falls. The findings of the thesis provide important considerations when designing future fall prevention programs.
Related Publications
Gebre AK & Lewis JR. Novel atherosclerotic cardiovascular causes of falls and fracture. HubLE Perspective, 2021. IFMRS – International Federation of Musculoskeletal Research Societies. https://www.huble.org/author/abadi-gebre/
Gebre, A. K., Sim, M., Rodríguez, A. J., Hodgson, J. M., Blekkenhorst, L. C., Szulc, P., ... Lewis, J. R. (2021). Abdominal aortic calcification is associated with a higher risk of injurious fall-related hospitalizations in older Australian women. Atherosclerosis, 328, 153-159.https://doi.org/10.1016/j.atherosclerosis.2021.05.003
https://ro.ecu.edu.au/ecuworkspost2013/10656/
Gebre, A. K., Sim, M., Dalla Via, J., Rodríguez, A. J., Hodgson, J. M., Bondonno, C. P., ... & Lewis, J. R. (2023). Measures of carotid atherosclerosis and fall-related hospitalization risk: The Perth Longitudinal Study of Ageing Women. Nutrition, Metabolism and Cardiovascular Diseases, 33(1), 95-104. https://doi.org/10.1016/j.numecd.2022.10.003
https://ro.ecu.edu.au/ecuworks2022-2026/1694/
Gebre, A. K., Sim, M., Dalla Via, J., Smith, C., Rodriguez, A. J., Hodgson, J. M., . . . Lewis, J. R. (2023). Association between high-sensitivity cardiac troponin I and fall-related hospitalisation in women aged over 70 years. Heart. Advance online publication. https://doi.org/10.1136/heartjnl-2023-322861
https://ro.ecu.edu.au/ecuworks2022-2026/2862/
Gebre, A. K., Sim, M., Dalla Via, J., Rodríguez, A. J., Zhu, K., Schousboe, J. T., . . . Lewis, J. R. (2023). Cardiovascular disease, muscle function, and long-term falls risk: The Perth longitudinal study of ageing women. Archives and Gerontology and Geriatrics, 107, article 104911. https://doi.org/10.1016/j.archger.2022.104911
https://ro.ecu.edu.au/ecuworks2022-2026/1693/
Gebre, A. K., Lewis, J. R., Leow, K., Szulc, P., Scott, D., Ebeling, P. R., . . . Rodríguez, A. J. (2023). Abdominal aortic calcification, bone mineral density and fractures: A systematic review and meta-analysis of observational studies. The Journals of Gerontology: Series A, 78(7), 1147–1154. https://doi.org/10.1093/gerona/glac171
https://ro.ecu.edu.au/ecuworks2022-2026/2469/
Gebre, A. K., Prince, R. L., Schousboe, J. T., Kiel, D. P., Thompson, P. L., Zhu, K., ... & Lewis, J. R. (2022). Calcaneal quantitative ultrasound is associated with all-cause and cardiovascular disease mortality independent of hip bone mineral density. Osteoporosis International, 33, 1557-1567. https://doi.org/10.1007/s00198-022-06317-x
https://ro.ecu.edu.au/ecuworks2022-2026/154/
