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Submissions from 2018

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Self-reported physical activity is associated with tau burden measured by positron emission tomography, Belinda M. Brown, Stephanie R. Rainey-Smith, Vincent Dore, Jeremiah J. Peiffer, Samantha C. Burnham, Simon M. Laws, Kevin Taddei, David Ames, Colin L. Masters, Christopher C. Rowe, Ralph N. Martins, and Victor L. Villemagne

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Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study, Sophie E. Holmes, Irina Esterlis, Carolyn M. Mazure, Yen Ying Lim, David Ames, Stephanie Rainey-Smith, Chris Fowler, Kathryn Ellis, Ralph N. Martins, Olivier Salvado, Vincent Dore, Victor L. Villemagne, Christopher C. Rowe, Simon M. Laws, Colin L. Masters, Robert H. Pietrzak, and Paul Maruff

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Ischemic stroke is associated with the pro-inflammatory potential of N-glycosylated immunoglobulin G, Di Liu, Zhongyao Zhao, Anxin Wang, Siqi Ge, Hao Wang, Xiaoyu Zhang, Qi Sun, Weijie Cao, Ming Sun, Lijuan Wu, Manshu Song, Yong Zhou, Wei Wang, and Youxin Wang

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Unravelling immunoglobulin G Fc N-glycosylation: A dynamic marker potentiating predictive, preventive and personalised medicine, Alyce Russell, Eric Adua, Ivo Ugrina, Simon Laws, and Wei Wang

Submissions from 2017

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Incorporation of suboptimal health status as a potential risk assessment for type II diabetes mellitus: a case-control study in a Ghanaian population, Eric Adua, Peter Roberts, and Wei Wang

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Innovation analysis on postgenomic biomarkers: Glycomics for chronic diseases, Eric Adua, Alyce Russell, Peter Roberts, Youxin Wang, Manshu Song, and Wei Wang

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Telomere length and accelerated biological aging in the China suboptimal health cohort: A case-control study, Mohamed Ali Alzain, Collins Otieno Asweto, Jie Zhang, Honghong Fang, Zhongyao Zhao, Xiuhua Guo, Manshu Song, Yong Zhou, Naibai Chang, Youxin Wang, and Wei Wang

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Development of the Aboriginal Communication Assessment After Brain Injury (ACAABI): A screening tool for identifying acquired communication disorders in Aboriginal Australians, Elizabeth Armstrong, Natalie Ciccone, Deborah J. Hersh, Judith Katzenellebogen, Juli Coffin, Sandra Thompson, Leon Flicker, Colleen Hayward, Deborah Woods, and Meaghan McAllister

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Serum high-density lipoprotein is associated with better cognitive function in a cross-sectional study of aging women, Kristyn Bates, Hamid R. Sohrabi, Stephanie Rainey-Smith, M Weinborn, Romola S. Bucks, Mark Rodrigues, John Beilby, Matthew Howard, Kevin Taddei, Georgia Martins, Athena Paton, Tejal Shah, Satvinder S. Dhaliwal, Johnathon K. Foster, Ian J. Martins, Nicola T. Lautenschlager, Frank L. Mastaglia, Samuel E. Gandy, and Ralph Martins

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The link between type 2 diabetes and neurodegeneration: Roles for amyloid-β, amylin, and tau proteins, Prashant Bharadwaj, Nadeeja Wijesekara, Milindu Liyanapathirana, Philip Newsholme, Lars Ittner, Paul Fraser, and Guiseppe Verdile

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Study protocol of the intense physical activity and cognition study: The effect of high-intensity exercise training on cognitive function in older adults, Belinda M. Brown, Stephanie Rainey-Smith, Natalie Castalanelli, Nicole Gordon, Shaun Markovic, Hamid R. Sohrabi, Michael Weinborn, Simon Laws, James Doecke, Kaikai Shen, Ralph Martins, and Jeremiah J. Peiffer

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Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease, Belinda M. Brown, Hamid R. Sohrabi, Kevin Taddei, Samantha Gardener, Stephanie Rainey-Smith, Jeremiah J. Peiffer, Chengjie Xiong, Anne M. Fagan, Tammie Benzinger, Virginia Buckles, Kirk I. Erickson, Roger Clarnette, Tejal Shah, Colin L. Masters, Michael Weiner, Nigel Cairns, Martin Rossor, Neill R. Graff-Radford, Stephen Salloway, Jonathan Vöglein, Christoph Laske, James Noble, Peter R. Schofield, Randall J. Bateman, John C. Morris, and Ralph Martins

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Abnormal methylation of imprinted genes and cigarette smoking: Assessment of their association with the risk of male infertility, Hao Dong, Youxin Wang, Zhikang Zou, Limin Chen, Chuanyun Shen, Shaoqiang Xu, Jie Zhang, Feifei Zhao, Siqi Ge, Qing Gao, Haixiang Hu, Manshu Song, and Wei Wang

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Human CAP10-like protein 46 kDa gene promotes malignancy in colorectal cancer, Honghong Fang, Qiaoyun Chu, Jie Zhang, Hao Wang, Xinwei Yu, Siqi Ge, Manshu Song, Lijuan Wu, Minglin Lang, Naibai Chang, Youxin Wang, and Wei Wang

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Immunoglobulin G N-Glycans as potential postgenomic biomarkers for hypertension in the Kazakh population, Qing Gao, Mamatyusupu Dolikun, Jerko Štambuk, Hao Wang, Feifei Zhao, Nizam Yiliham, Youxin Wang, Irena Trbojević-Akmačić, Jie Zhang, Honghong Fang, Yang Sun, Hongli Peng, Zhongyao Zhao, Di Liu, Jiaonan Liu, Qihuan Li, Qi Sun, Lijuan Wu, Gordan Lauc, Wei Wang, and Manshu Song

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Contribution of genetic polymorphisms and haplotypes in DRD2, BDNF, and opioid receptors to heroin dependence and endophenotypes among the Han Chinese, Xuan Gao, Youxin Wang, Minglin Lang, Li Yuan, Albert Reece, and Wei Wang

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Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes, Toma Keser, Ivan Gornik, Frano Vuckovic, Najda Selak, Tamara Pavic, Edita Lukic, Hrvoje Gasparovic, Bojan Biocina, Therese Tilin, Annika Wennerstrom, Satu Mannisto, Veikko Salomaa, Aki Havulinna, Wei Wang, James F. Wilson, Nishi Charutvedi, Markus Perola, Harry Campbell, Gordan Lauc, and Olga Gornik

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The indirect efficacy comparison of DNA methylation in sputum for early screening and auxiliary detection of lung cancer: A meta-analysis, Di Liu, Hongli Peng, Qi Sun, Zhongyoa Zhao, Xinwei Yu, Siqi Ge, Hao Wang, Honghong Fang, Qing Gao, Jiaonan Liu, Lijuan Wu, Manshu Song, and Youxin Wang

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Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma, Ashleigh C. McEvoy, Leslie Calapre, Michelle Pereira, Tindaro M. Giardina, Cleo Robinson, Muhammad A. Khattak, Tarek M. Meniawy, Antonia L. Pritchard, Nicholas K. Hayward, Benhur Amanuel, Michael J. Millward, Mel R. Ziman Dr, and Elin S. Gray

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Screening for potential serum-based proteomic biomarkers for human type 2 diabetes mellitus using MALDI-TOF MS, Qiutao Meng, Siqi Ge, Wenhua Yan, Ruisheng Li, Jingtao Dou, Haibing Wang, Baoan Wang, Qingwei Ma, Yong Zhou, Manshu Song, Xinwei Yu, Hao Wang, Xinghua Yang, Fen Liu, Mohamed Ali Alzain, Yuxiang Yan, Ling Zhang, Lijuan Wu, Feifei Zhao, Yan He, Xiuhua Guo, Feng Chen, Weizhuo Xu, Monique Garcia, Desmond D. Menon, Youxin Wang, Yiming Mu, and Wei Wang

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Plasma cortisol, brain amyloid-β, and cognitive decline in preclinical Alzheimer’s disease: A 6-year prospective cohort study, Robert H. Pietrzak, Simon Laws, Yen Ying Lim, Sophie J. Bender, Tenielle Porter, James Doecke, David Ames, Chrisopher Fowler, Colin L. Masters, Lidija Milicic, Stephanie Rainey-Smith, Victor L. Villemagne, Christopher C. Rowe, Ralph Martins, and Paul Maruff

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Effects of different exercise modalities on fatigue in prostate cancer patients undergoing androgen deprivation therapy: a year-long randomised controlled trial, Dennis Taaffe, Robert Newton, Nigel Spry, David Joseph, Suzanne K. Chambers, Robert Gardiner, Brad Wall, Prue Cormie, Kate Bolam, and Daniel A. Galvao

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Exercise improves VO2max and body composition in androgen deprivation therapy-treated prostate cancer patients, Bradley A. Wall, Daniel A. Galvão, Naeem N. Fatehee, Dennis R. Taaffe, Nigel A. Spry, David J. Joseph, Jeffrey J. Herbert, and Robert U. Newton

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Serum peptidome profiling for the diagnosis of colorectal cancer: Discovery and validation in two independent cohorts, Hao Wang, Chenghua Luo, Shengtao Zhu, Honghong Fang, Qing Gao, Siqi Ge, Haixia Qu, Qingwei Ma, Hongwei Ren, Youxin Wang, and Wei Wang

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Association between ideal cardiovascular health metrics and suboptimal health status in Chinese population, Youxin Wang, Xiaoxue Liu, Jing Qiu, Hao Wang, Di Liu, Zhongyao Zhao, Manshu Song, Qiaofeng Song, Xizhu Wang, Yong Zhou, and Wei Wang

Submissions from 2016

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Validation and characterization of a novel peptide that binds monomeric and aggregated β-Amyloid and inhibits the formation of neurotoxic oligomers, Renae K. Barr, Guiseppe Verdile, Linda K. Wijaya, Michael Morici, Kevin Taddei, Veer Gupta, Steve Pedrini, Liang Jin, Joseph A. Nicolazzo, Erin Knock, Paul E. Fraser, and Ralph Martins

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Cerebral glucose metabolism is associated with verbal but not visual memory performance in community-dwelling older adults, Samantha Gardener, Hamid R. Sohrabi, Kai-kai Shen, Stephanie Rainey-Smith, Michael Weinborn, Kristyn A. Bates, Tejal Shah, Jonathan K. Foster, Nat Lenzo, Olivier Salvado, Christoph Laske, Simon M. Laws, Kevin Taddei, Giuseppe Verdile, and Ralph Martins

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A randomized controlled trial of very early rehabilitation in speech after stroke, Erin Godecke, Elizabeth Armstrong, Tapan Rai, Sandy Middleton, Natalie Ciccone, Anne Whitworth, Miranda Rose, Audrey Holland, Fiona Ellery, Graeme Hankey, Dominique Cadilhac, and Julie Bernhardt

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Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging, Veer Gupta; James D. Doecke; Eugene Hone; Steve Pedrini; Simon M. Laws; Madhav Thambisetty; Ashley Bush,; Christopher C. Rowe; Victor L. Villemagne; David Ames; Colin L. Masters; Stuart Lance Macaulay; Alan Rembach; Stephanie R. Rainey-Smith; and Ralph N. Martins

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β-Amyloid, APOE and BDNF genotype, and depressive and anxiety symptoms in cognitively normal older women and men, Sophie E. Holmes, Irina Esterlis, Carolyn M. Mazure, Yenying Lim, David J. Ames, Stephanie R. Rainey-Smith, Ralph N. Martins, Olivier Salvado, Vincent Doré, Victor L. Villemagne, Christopher C. Rowe, Simon M. Laws, C. L. Masters, Paul T. Maruff, and Robert H. Pietrzak

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Missing voices: Profile and Extent of Acquired Communication Disorders in Aboriginal and Non-Aboriginal Adult Stroke Survivors in Western Australia Using Linked Administrative Records, Judith Katzenellenbogen, Emily Atkins, S C. Thompson, Deborah Hersh, Juli Coffin, Leon Flicker, Colleen Hayward, Natalie Ciccone, Deborah Woods, Meaghan McAllister, and Elizabeth Armstrong

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Association between IGF2BP2 polymorphisms and type 2 diabetes mellitus: A case-control study and meta-analysis, Ping Rao, Hao Wang, Honghong Fang, Qing Gao, Jie Zhang, Manshu Song, Yong Zhou, Youxin Wang, and Wei Wang

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Validation of Type 2 Diabetes Risk Variants Identified by Genome-Wide Association Studies in Northern Han Chinese, Ping Rao, Yong Zhou, Siqi Ge, Anxin Wang, Xinwei Yu, Mohamed Ali Alzain, Andrea K. Veronica, Jing Qiu, Manshu Song, Jie Zhang, Hao Wang, Honghong Fang, Qing Gao, Youxin Wang, and Wei Wang

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Glycan biomarkers for rheumatoid arthritis and its remission status in Han Chinese patients, Andrea Sebastian, Mohamed Ali Alzain, Collins Asweto, Haicheng Song, Liufu Cui, Xinwei Yu, Siqi Ge, Hao Dong, Ping Rao, Hao Wang, Honghong Fang, Qing Gao, Jie Zhang, Dian He, Xiuhua Guo, Manshu Song, Youxin Wang, and Wei Wang

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China suboptimal health cohort study: Rationale, design and baseline characteristics, Youxin Wang, Siqi Ge, Yuxiang Yan, Anxin Wang, Zhongyao Zhao, Xinwei Yu, Jing Qui, Mohamed Ali Alzain, Hao Wang, Honghong Fang, Qing Gao, Manshu Song, Jie Zhang, Yong Zhou, and Wei Wang

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The association between glycosylation of immunoglobulin G and hypertension, Youxin Wang, Lucija Klarić, Xinwei Yu, Kujtim Thaqi, Jing Dong, Mislav Novokmet, Jim Wilson, Ozren Polasek, Youqin Liu, Jasminka Krištić, Siqi Ge, Maja Pučić-Baković, Lijuan Wu, Yong Zhou, Ivo Ugrina, Manshu Song, Jie Zhang, Xiuhua Guo, Qiang Zeng, Igor Rudan, Harry Campbell, Yurii Aulchenko, Gordan Lauc, and Wei Wang

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Profiling IgG N-glycans as potential biomarker of chronological and biological ages: A community-based study in a Han Chinese population, Xinwei Yu, Youix Wang, Jasminka Krištić, Jing Dong, Xi Chu, Siqi Ge, Hao Wang, Honghong Fang, Qing Gao, Di Lui, Zhongya Zhao, Hongli Peng, Maja P. Baković, Lijuan Wu, Manshu Song, Igor Rudan, Harry Campbell, Gordan Lauc, and Wei Wang

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The Uyghur population and genetic susceptibility to type 2 diabetes: potential role for variants in CAPN10, APM1 and FUT6 genes, Feifei Zhao, Dolikun Mamatyusupu, Youxin Wang, Honghong Fang, Hao Wang, Qing Gao, Hao Dong, Siqi Ge, Xinwei Yu, Jie Zhang, Lijuan Wu, Manshu Song, and Wei Wang

Submissions from 2015

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Study Protocol: Missing Voices – Communication Difficulties after Stroke and Traumatic Brain Injury in Aboriginal Australians, Elizabeth Armstrong, Deborah Hersh, Judith M. Katzenellenbogen, Juli Coffin, Sandra C. Thompson, Natalie Ciccone, Colleen Hayward, Leon Flicker, Deborah Woods, and Meaghan McAllister

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Circulating Melanoma Cell Subpopulations: Their Heterogeneity and Differential Responses to Treatment, Elin S. Gray, Anna L. Reid, Samantha Bowyer, Leslie Calapre, Kelvin Siew, Robert Pearce, Lester Cowell, Markus H. Frank, Michael Millward, and Mel R. Ziman Dr

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Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma, Elin S. Gray, Helen Rizos, Anna L. Reid, Suzanah Boyd, Michelle Pereira, Johnny Lo, Varsha Tembe, James Freeman, Jenny Lee, Richard Scolyer, Kelvin Siew, Chris Lomma, Adam Cooper, Muhammad Khattak, Tarek Meniawy, Georgina Long, Matteo Carlino, Michael Millward, and Mel R. Ziman

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Follow-up Plasma Apolipoprotein e Levels In The Australian Imaging, Biomarkers And Lifestyle Flagship Study of Ageing (AIBL) Cohort, Veer B. Gupta, V.B; Andrea C. Wilson; Samantha Burnham; Eugene Hone; Steve Pedrini; Simon M. Laws; Wei L.F. Lim; Alan Rembach; Stephanie Rainey-Smith; David Ames; Lynne Cobiac; S L. MacAulay; Colin L. Masters; Christopher C. Rowe; Ashley I. Bush; Ralph Martins; and AIBL Research Group

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A Depressive Endophenotype Of Poorer Cognition Among Cognitively Healthy Community-dwelling Adults: Results From The Western Australia Memory Study, Leigh A. Johnson, Hamid R. Sohrabi, James R. Hall, Kevin Taddei, Melissa Edwards, Sid E. O'Bryant, and Ralph Martins

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Detection of BRAF-V600E and V600K in melanoma circulating tumour cells by droplet digital PCR, Anna L. Reid, James B. Freeman, Michael Millward, Melanie Ziman, and Elin S. Gray

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Bone Mineral Density, Adiposity, And Cognitive Functions, Hamid R. Sohrabi, Kristyn A. Bates, Michael Weinborn, Romola S. Bucks, Stephanie R. Rainey-Smith, Mark A. Rodrigues, Sabine M. Bird, Belinda M. Brown, John Beilby, Matthew Howard, Arthur Criddle, Megan Wraith, Kevin Taddei, Georgia Martins, Athena Paton, Tejal Shah, Satvinder S. Dhaliwal, Pankaj D. Mehta, Jonathan K. Foster, Ian J. Martins, Nicola T. Lautenschlager, Francis Mastaglia, Simon Laws, and Ralph Martins

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The Uyghur Population And Genetic Susceptibility To Type 2 Diabetes: Potential Role For Variants In CDKAL1, JAZF1, and IGF1 Genes, Manshu Song, Feifei Zhao, Longjin Ran, Mamatyusupu Dolikun, Lijuan Wu, Lijuan Ge, Hao Dong, Qing Gao, Yanchun Zhai, Ling Zhang, Yuxiang Yan, Fen Liu, Xinghua Yang, Xiuhua Guo, Youxin Wang, and Wei Wang

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The Impact Of Luteinizing Hormone And Testosterone On Beta Amyloid (Aβ) Accumulation: Animal And Human Clinical Studies, Giuseppe Verdile, Prita R. Asih, Anna M. Barron, Eka J. Wahjoepramono, Lars M. Ittner, and Ralph Martins

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The role of type 2 diabetes in neurodegeneration, Giuseppe Verdile, Stephanie J. Fuller, and Ralph N. Martins

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Reduced cardiovascular capacity and resting metabolic rate in men with prostate cancer undergoing androgen deprivation: A comprehensive cross-sectional investigation, Bradley Wall, Daniel A. Galvao, Naeem Fatehee, Dennis Taaffe, Nigel Spry, David Joseph, and Robert Newton

Submissions from 2014

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Improving sexual health in men with prostate cancer: Randomised controlled trial of exercise and psychosexual therapies, Prue Cormie, Suzanne K. Chambers, Robert U. Newton, Robert A. Gardiner, Nigel Spry, Dennis R. Taaffe, David Joseph, M Akhlil Hamid, Peter Chong, David Hughes, Kyra Hamilton, and Daniel A. Galvão

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Messages that increase women's intentions to abstain from alcohol during pregnancy: Results from quantitative testing of advertising concepts, Kathryn E. France, Robert J. Donovan, Carol Bower, Elizabeth J. Elliott, Janet M. Payne, Heather D'Antoine, and Anne E. Bartu

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Monitoring changes in circulating tumour cells as a prognostic indicator of overall survival and treatment response in patients with metastatic melanoma, Dragana Klinac, Elin S. Gray, James B. Freeman, Anna Reid, Samantha Bowyer, Michael Millward, and Mel Ziman

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The involvement of lipids in alzheimer's disease, Wei L. Lim, Ian J. Martins, and Ralph N. Martins

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Maximal exercise testing of men with prostate cancer being treated with androgen deprivation therapy, Bradley A. Wall, Daniel A. Galvão, Naeem Fatehee, Dennis R. Taaffe, Nigel Spry, David Joseph, and Robert U. Newton

Submissions from 2013

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Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer’s and other neurodegenerative diseases, P R. Bharadwaj, K A. Bates, T Porter, E Teimouri, G Perry, J W. Steele, S Gandy, D Groth, R N. Martins, and Giuseppe Verdile

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Promoting Abstinence From Alcohol During Pregnancy: Implications From Formative Research, Kathryn France, Robert Donovan, Nadine Henley, Carol Bower, Elizabeth Elliott, Janet Payne, Heather D'Antoine, and Anne Bartu

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Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice, Wei Ling F. Lim, Sin Man Lam, Guanghou Shui, Alinda Mondal, Daniel Ong, Xinrui Duan, Rhona Creegan, Ian J. Martins, Matthew J. Sharman, Kevin Taddei, Giuseppe Verdile, Markus R. Wenk, and Ralph Martins

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Increased Risk for Obesity and Diabetes with Neurodegeneration in Developing Countries, Ian J. Martins

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The acceleration of aging and Alzheimer’s disease through the biological mechanisms behind obesity and type II diabetes, Ian J. Martins, Wei Ling F. Lim, Andrea C. Wilson, Simon M. Laws, and Ralph Martins

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Molecular Insights into Appetite Control and Neuroendocrine Disease as Risk Factors for Chronic Diseases in Western Countries, I J. Martins, Rhona Creegan, W. L. F. Lim, and Ralph Martins

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Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain, J Steele, S Ju, M Lachenmayer, J Liken, A Stock, S Kim, L Delgado, I Alfaro, S Bernales, G Verdile, P Bharadwaj, V Gupta, R Barr, A Friss, G Dolios, R Wang, D Ringe, A Protter, R Martins, M Ehrlich, Z Yue, G Petsko, and S Gandy

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Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model, J Steele, M Lachenmayer, S Ju, A Stock, J Liken, S Kim, L Delgado, I Alfaro, S Bernales, G Verdile, P Bharadwaj, V Gupta, R Barr, A Friss, G Dolios, R Wang, D Ringe, P Fraser, D Westaway, P St George-Hyslop, P Szabo, N Relkin, J Buxbaum, C Glabe, A Protter, R Martins, M Ehrlich, G Petsko, Z Yue, and S Gandy

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Serological autoantibodies as diagnostic cancer biomarkers - A review, Pauline Zaenker and Melanie R. Ziman

Submissions from 2012

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Latrepirdine (Dimebon (TM)) Enhances Autophagy and Reduces Intracellular GFP-A beta(42) Levels in Yeast, Prashant Bharadwaj, Giuseppe Verdile, Renae Barr, Veer Gupta, John Steele, M. Lenard Lachenmayer, Zhenyu Yue, Michelle Ehrlich, Gregory Petsko, Shulin Ju, Dagmar Ringe, Sonia Sankovich, Joanne Caine, Ian Macreadie, Sam Gandy, and Ralph Martins

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Evaluation of a multi-marker immunomagnetic enrichment assay for the quantification of circulating melanoma cells, James Freeman, Elin Gray, Michael Milward, Robert Pearce, and Melanie Ziman

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Sirtuin-1 mediates the obesity induced risk of common degenerative diseases: Alzheimer's disease, coronary artery disease and type 2 diabetes, Ian Martins, Andrea Wilson, Wei Ling Lim, Simon Laws, Stephanie Fuller, and Ralph Martins

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Markers of circulating tumour cells in the peripheral blood of patients with melanoma correlate with disease recurrence and progression, A Reid, M Millward, R Pearce, M Lee, M Frank, A Ireland, L Monshizadeh, T Rai, P Heenan, S Medic, P Kumarasinghe, and M Ziman